Experimental Research on the Effect of L-carnitine and Physical Exercise on the Rats’ Skeletal Muscle Mitochondrial Respiratory Chain Enzyme Complex Activity

نویسنده

  • Yunlong Tong
چکیده

Mitochondria are where the oxidative phosphorylation of eukaryotic cells provides energy and generates more ATP for the movements of organism. To discuss the effect of L-carnitine and physical exercise on the rat’s skeletal muscle mitochondrial respiratory chain enzyme complex activity, 40 male Whister rats were classified into four groups at random, each consisting of 10 ones. The groups were control group (I), physical exercise group (II), L-carnitine group (III) and L-carnitine+ physical exercise group(IV). Results show that L-carnitine or physical exercise may improve the function of rats’ skeletal muscle mitochondrion and respiratory chain immediately after their exhaustive exercise, however, combination of L-carnitine with physical exercises bring better results; and Physical exercise and L-carnitine have synergistic effect in improving the function of rats’ skeletal muscle Mitochondrion and respiratory chain immediately after their exhaustive exercise. The experiment results demonstrate that experimentation basis and data can be provided for supplementing nutrients and exercise loads can be applied to improving the respiratory functions of the mitochondria and relieving the fatigue from sports.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Aerobic Training and L- Carnitine on BCL2 and Mitochondrial Enzymes of Rat\'s Kidney

Objective: Diabetes causes free radical production, oxidative stress and alterations in mitochondrial enzymes and apoptosis. The purpose of this study was to investigate the effect of aerobic exercise and consumption of L-carnitine on BCL2 and some mitochondrial enzymes of the kidney in diabetic rats. Materials and Methods: In this experimental study, 45 male wistar rats (200-300 gr) were simp...

متن کامل

Long-term, high-dose aspirin therapy increases the specific activity of complex III of mitochondrial respiratory chain in the kidney of diabetic rats

Introduction: One of the main mechanisms by which diabetic complications occur is an alteration of the structure and function of proteins due to hyperglycemia. Aspirin (ASA) affects cellular pathways through different mechanisms, including glycation inhibition and antioxidant activity. The aim of the present study, as a follow up to our previous one, is to investigate the effect of long-term, h...

متن کامل

Effect of carnitine supplementation on mitochondrial enzymes in liver and skeletal muscle of rat after dietary lipid manipulation and physical activity.

Effect of carnitine supplementation in enhancing fat utilization was investigated by looking into its effects on mitochondrial respiratory enzymes activity in liver and muscle as well as on membrane fatty acid profile in rats fed with hydrogenated fat (HF) and MUFA-rich peanut oil (PO) with or without exercise. Male Wistar rats were fed HF-diet (4 groups, 8 rats in each group) or PO-diet (4 gro...

متن کامل

The Effect of Aerobic Exercise & L-Carnitine Consumption on Diabetes-Induced Apoptosis & Oxidative Stress Factors in Rat

Objective: The use of non-enzymatic antioxidants in the form of dietary supplements has a positive effect on reducing oxidative stress, and preventing apoptosis as they interrupt free radicals. The aim of this study was to investigate the aerobic exercise and L-carnitine consumption impacts on diabetes induced apoptosis, oxidative stress factors, and mitochondrial enzymes in rats. Materials an...

متن کامل

Effect of Aerobic Training and L-Carnitine Supplementation on Hepatic Oxidative Stress Factors in Diabetic Rat

Objective: The use of non-enzymatic antioxidants in food supplements and proper exercise can have a positive effect on decreasing oxidative stress by free radical hunting. The purpose of this study was to investigate the effect of aerobic training and L-carnitine supplementation on some of the oxidative stress factors in the liver of diabetic rats. Materials and Methods: In this experimental s...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016